Primary high grade papillary serous carcinoma of cervix: report of a case

سال انتشار: 1401
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 29

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شناسه ملی سند علمی:

JR_CJM-3-2_005

تاریخ نمایه سازی: 30 اردیبهشت 1403

چکیده مقاله:

Introduction: Papillary Serous Cervical Carcinoma (PSCC) is a very rare type of primary adenocarcinoma of the cervix. Herein, we report such a case of PSCC and describe its presentation and treatment.Case presentation:Our patient was a ۶۵-year-old woman presented with vaginal spotting ۱۴ years after menopause. Vaginal examination was not remarkable; however, transvaginal ultrasound showed cervical irregularity. A Pap smear was done for her that revealed atypical cells. The patient underwent total abdominal hysterectomy and bilateral salpingo-oophorectomy. Pathologic examination and Immunohistochemical study disclosed PSCC. Metastatic evaluations including abdomen and pelvic MRI and chest CT scan were negative. Therefore, pathologic stage was IB۱. Due to inadequate lymph node dissection, the patient received adjuvant external beam radiotherapy (۴۵ Gy in ۲۵ fractions). Subsequently, adjuvant endocavitary brachytherapy (۳ fractions of ۴ Gy) was delivered; however, she refused to receive any adjuvant chemotherapy. After ۱۲ months she is well and is doing her regular daily life.Conclusions: PSCC is a rare case and although Radiotherapy is usually done for patients, its treatment is not well known.

نویسندگان

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Associate Professor in Radiation Oncology, Radiotherapy Oncology Department, Shiraz University of Medical Sciences, Shiraz, Iran

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Assistant Professor in radiation Oncology, Department of Radiation oncology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran

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Radiation Oncologist, Radiation Oncology Department, school of medicine, Shiraz University of Medical Sciences, Shiraz, Iran

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Professor in Radiation Oncology, Colorectal Research Center, school of medicine, Shiraz, Iran

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Assistant Professor of Dermatopathology, Department of Pathology, School of Medicine, Maternal-fetal Medicine Research Center, Shiraz University of Medical Sciences

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Assistant Professor of Pathology, Department of Pathology, School of Medicine, Vali Asr Hospital, Fasa University of Medical Science

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Professor in Radiation Oncology, Breast Diseases Research Center, school of medicine, Shiraz University of Medical Sciences, Shiraz, Iran

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Professor in radiation Oncology, Department of Radiation oncology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran

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Breast Diseases Research Center, school of medicine, Shiraz University of Medical Sciences, Shiraz, Iran